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Progressive Vaccinia: General

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Click here to Zoom Example of progressive vaccinia lesions in a child with T-cell deficiency
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Progressive vaccinia is one of the most severe complications of smallpox vaccination. It is almost always life threatening. 

Progressive vaccinia is the preferred designation for this complication although, in the past, it has sometimes been termed:

•  Vaccinia necrosum
•  Vaccinia gangrenosa
•  Disseminated vaccinia

Rare in the past, it may be a greater threat today, given the larger proportion of susceptible persons in the population.

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