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Bioterrorism Agents/Diseases

A to Z  |  By category

On this page:

  • Category A (definition below)

  • Anthrax (Bacillus anthracis)

  • Botulism (Clostridium botulinum toxin)

  • Plague (Yersinia pestis)

  • Smallpox (variola major)

  • Tularemia (Francisella tularensis)

  • Viral hemorrhagic fevers (filoviruses [e.g., Ebola, Marburg] and arenaviruses [e.g., Lassa, Machupo])

  • Category B (definition below)

  • Brucellosis (Brucella species)

  • Epsilon toxin of Clostridium perfringens

  • Food safety threats (e.g., Salmonella species, Escherichia coli O157:H7, Shigella)

  • Glanders (Burkholderia mallei)

  • Melioidosis (Burkholderia pseudomallei)

  • Psittacosis (Chlamydia psittaci)

  • Q fever (Coxiella burnetii)

  • Ricin toxin from Ricinus communis (castor beans)

  • Staphylococcal enterotoxin B

  • Typhus fever (Rickettsia prowazekii)

  • Viral encephalitis (alphaviruses [e.g., Venezuelan equine encephalitis, eastern equine encephalitis, western equine encephalitis])

  • Water safety threats (e.g., Vibrio cholerae, Cryptosporidium parvum)

  • Category C (definition below)

  • Emerging infectious diseases such as Nipah virus and hantavirus

Category A Diseases/Agents

The U.S. public health system and primary healthcare providers must be prepared to address various biological agents, including pathogens that are rarely seen in the United States. High-priority agents include organisms that pose a risk to national security because they

  • can be easily disseminated or transmitted from person to person;
  • result in high mortality rates and have the potential for major public health impact;
  • might cause public panic and social disruption; and
  • require special action for public health preparedness.

Category B Diseases/Agents

Second highest priority agents include those that

  • are moderately easy to disseminate;
  • result in moderate morbidity rates and low mortality rates; and
  • require specific enhancements of CDC's diagnostic capacity and enhanced disease surveillance.

Category C Diseases/Agents

Third highest priority agents include emerging pathogens that could be engineered for mass dissemination in the future because of

  • availability;
  • ease of production and dissemination; and
  • potential for high morbidity and mortality rates and major health impact.


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